ea0070aep897 | Thyroid | ECE2020
Pant Vivek
, Baral Suman
Introduction: Biotin-streptavidin detection method is used in a majority of commercial immunoassay. Biotinylated antibodies (capture antibodies) bind strongly to streptavidin that anchors those antibodies to the solid phase of the assay. Thus, high biotin concentration in the serum interferes with this bond and alters the expected results. Clinical history of patient and additional laboratory test is important for troubleshooting of discordant thyroid function test result....